RS3PE and the role of ultrasound. A case report and brief review of the literature

Remitting seronegative symmetric synovitis with pitting edema (RS3PE) is a rare syndrome characterised by acute onset of symmetrical distal and tenosynovitis, associated severe the dorsum hands feet, seronegativity for autoimmunity dramatic response to glucocorticoids. First described McCarty et al. in 1985, RS3PE reported mostly elderly males, but it can also rarely occur young people. Although was initially regarded as form rheumatoid arthritis (RA), now considered clinical distinct entity that be other rheumatologic conditions or secondary underlying diseases, such cancer. As revealed magnetic resonance imaging (MRI), typical landmark extensor tenosynovitis. Due extensive subcutaneous extremities, assessment tenosynovitis difficult. On hand, use MRI expensive, time-consuming requires experienced staffs. Musculoskeletal ultrasound (MSUS) may viable, reliable cost-effective tool evaluation patients. We hereby report case an 84 year-old woman presenting bilateral hand wrist swelling morning stiffness. Clinical examination, laboratory tests led diagnosis RS3PE. The aim this discuss role MSUS purpose differential compared conditions.